Assay Detail
Functional
CHEMBL5042320
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Antiproliferative activity against human SW480 cells assessed as cell growth inhibition and measured after 72 hrs by CCK8 assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW480 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydrophobic Tagging-Induced Degradation of PDEδ in Colon Cancer Cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 5.04 | 5.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5094121 | — | — | 1 | 5.32 |
| CHEMBL5084808 | — | — | 1 | 5.27 |
| CHEMBL5077941 | — | — | 1 | 5.25 |
| CHEMBL5072868 | — | — | 1 | 5.16 |
| CHEMBL5079726 | — | — | 1 | 5.10 |
| CHEMBL5086138 | — | — | 1 | 5.00 |
| CHEMBL5092958 | — | — | 1 | 4.85 |
| CHEMBL1387422 | — | — | 1 | 4.74 |
| CHEMBL5092661 | — | — | 1 | 4.70 |
| CHEMBL5082602 | — | — | 1 | - |
| CHEMBL5087129 | — | — | 1 | - |
| CHEMBL5083136 | — | — | 1 | - |
| CHEMBL5084153 | — | — | 1 | - |
| CHEMBL5089219 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5094121 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL5084808 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL5077941 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL5072868 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL5079726 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL5086138 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL5092958 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL1387422 | — | IC50 | = | 18300.0 | nM | 4.74 |
| CHEMBL5092661 | — | IC50 | = | 19800.0 | nM | 4.70 |
| CHEMBL5082602 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5087129 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5083136 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5084153 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5089219 | — | IC50 | > | 100000.0 | nM | - |