Assay Detail
Binding
CHEMBL5042378
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H] DPCPX from mouse adenosine A1 receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Selective A<sub>3</sub> Adenosine Receptor Antagonist Radioligand for Human and Rodent Species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.19 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5081520 | — | — | 1 | 6.60 |
| CHEMBL2181976 | — | — | 1 | 6.39 |
| CHEMBL5086258 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5081520 | — | Ki | = | 252.0 | nM | 6.60 |
| CHEMBL2181976 | — | Ki | = | 411.0 | nM | 6.39 |
| CHEMBL5086258 | — | Ki | = | 2640.0 | nM | 5.58 |