Assay Detail
Binding
CHEMBL5042409
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Binding affinity to human adenosine A3 receptor measured by radioligand binding assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Selective A<sub>3</sub> Adenosine Receptor Antagonist Radioligand for Human and Rodent Species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.82 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL133566 | — | — | 1 | 6.00 |
| CHEMBL302765 | — | — | 1 | 5.95 |
| CHEMBL27376 | — | — | 1 | 5.85 |
| CHEMBL1625681 | — | — | 1 | 5.46 |
| CHEMBL3407784 | — | — | 1 | - |
| CHEMBL119709 | IB-MECA | — | 1 | - |
| CHEMBL431733 | NAMODENOSON | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL133566 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL302765 | — | Ki | = | 1130.0 | nM | 5.95 |
| CHEMBL27376 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL1625681 | — | Ki | = | 3510.0 | nM | 5.46 |
| CHEMBL3407784 | — | Ki | = | 700.0 | nM | - |
| CHEMBL119709 | IB-MECA | Ki | = | 1800.0 | nM | - |
| CHEMBL431733 | NAMODENOSON | Ki | = | 1400.0 | nM | - |