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Assay Detail

CHEMBL5043468

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of P-RNAase L K164E mutant expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery.
Tang J, Dong B, Liu M, Liu S, Niu X, Gaughan C, Asthana A, Zhou H, Xu Z, Zhang G, Silverman RH, Huang H.
J Med Chem (2022) 65 : 1445 -1457
PubMed 34841869 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.99 5.99

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL251254 HYPEROSIDE 1 5.99

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL251254 HYPEROSIDE IC50 = 1020.0 nM 5.99