Assay Detail
Functional
CHEMBL5048127
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Cytotoxicity against human U-251 cells by sulforhodamine B assay
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-251 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cyclotides Chemosensitize Glioblastoma Cells to Temozolomide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.53 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4285275 | — | — | 2 | 6.10 |
| CHEMBL4211294 | — | — | 1 | 4.96 |
| CHEMBL5090055 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4285275 | — | IC50 | = | 790.0 | nM | 6.10 |
| CHEMBL4211294 | — | IC50 | = | 10880.0 | nM | 4.96 |
| CHEMBL4285275 | — | IC50 | = | 17.05 | ug.mL-1 | - |
| CHEMBL5090055 | — | IC50 | = | 37.18 | ug.mL-1 | - |