Assay Detail
Binding
CHEMBL5049013
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Inhibition of human MMP-14
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
<i>N</i>-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.53 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5086580 | — | — | 1 | 4.92 |
| CHEMBL5079481 | — | — | 1 | 4.51 |
| CHEMBL5090517 | — | — | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5086580 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL5079481 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL5090517 | — | IC50 | = | 68000.0 | nM | 4.17 |