Assay Detail
ADMET
CHEMBL5049189
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Binding affinity to human serum albumin assessed as dissociation rate constant by surface plasmon resonance assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Tissue | Serum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 4.90 | 5.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1464 | WARFARIN | 4.0 | 1 | 5.26 |
| CHEMBL5082824 | — | — | 1 | 4.95 |
| CHEMBL4464759 | — | — | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1464 | WARFARIN | Kd | = | 5500.0 | nM | 5.26 |
| CHEMBL5082824 | — | Kd | = | 11300.0 | nM | 4.95 |
| CHEMBL4464759 | — | Kd | = | 31700.0 | nM | 4.50 |