Assay Detail
Binding
CHEMBL5050709
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to PPARgamma (unknown origin) by lanthascreen TR-FRET assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.16 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5070753 | — | — | 1 | 7.62 |
| CHEMBL121 | ROSIGLITAZONE | 4.0 | 1 | 7.05 |
| CHEMBL3348830 | — | — | 1 | 6.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5070753 | — | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL121 | ROSIGLITAZONE | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL3348830 | — | IC50 | = | 154.0 | nM | 6.81 |