Assay Detail
Functional
CHEMBL5051071
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MDA-MB-157 cells after 72 hrs by Cell Titer Glo assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-157 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Highly potent tacc3 inhibitor as a novel anticancer drug candidate
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.99 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5085062 | — | — | 1 | 6.48 |
| CHEMBL3186037 | — | — | 1 | 5.74 |
| CHEMBL5080850 | — | — | 1 | 5.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5085062 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL3186037 | — | IC50 | = | 1823.0 | nM | 5.74 |
| CHEMBL5080850 | — | IC50 | = | 1822.0 | nM | 5.74 |