Assay Detail
Binding
CHEMBL5051276
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Cav3.3 in human HEK293 cells measured under hyperpolarizing conditions by FLIPR assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-dependent T-type calcium channel subunit alpha-1I (CHEMBL5558) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Treating essential tremor using (r)-2-(4-isopropylphenyl)-n-(1-(5-(2,2,2-trifluoroethoxy)pyridin-2-yl)ethyl)acetamide
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.79 | 6.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1684950 | SUVECALTAMIDE | 2.0 | 1 | 6.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1684950 | SUVECALTAMIDE | IC50 | = | 161.0 | nM | 6.79 |