Assay Detail
Binding
CHEMBL5051277
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Cav3.3 (unknown origin) at holding potential (Vh) -80 mV and measured by whole-cell voltage-camp assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-dependent T-type calcium channel subunit alpha-1I (CHEMBL5558) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Treating essential tremor using (r)-2-(4-isopropylphenyl)-n-(1-(5-(2,2,2-trifluoroethoxy)pyridin-2-yl)ethyl)acetamide
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.08 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1684950 | SUVECALTAMIDE | 2.0 | 1 | 7.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1684950 | SUVECALTAMIDE | IC50 | = | 84.0 | nM | 7.08 |