Assay Detail
Binding
CHEMBL5052860
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards GIP receptor in human HEK293 cells measured by fluorescence assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gastric inhibitory polypeptide receptor (CHEMBL4383) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Peptide targeting gip and glp-2 receptors for treating bone disorders
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 8.71 | 9.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5072364 | — | — | 1 | 9.85 |
| CHEMBL5077951 | — | — | 1 | 9.14 |
| CHEMBL5075905 | — | — | 1 | 9.04 |
| CHEMBL5087366 | — | — | 1 | 9.01 |
| CHEMBL5090950 | — | — | 1 | 8.98 |
| CHEMBL5083589 | — | — | 1 | 8.92 |
| CHEMBL5078233 | — | — | 1 | 8.56 |
| CHEMBL5078651 | — | — | 1 | 8.34 |
| CHEMBL5088990 | — | — | 1 | 7.88 |
| CHEMBL5089388 | — | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5072364 | — | IC50 | = | 0.14 | nM | 9.85 |
| CHEMBL5077951 | — | IC50 | = | 0.72 | nM | 9.14 |
| CHEMBL5075905 | — | IC50 | = | 0.91 | nM | 9.04 |
| CHEMBL5087366 | — | IC50 | = | 0.97 | nM | 9.01 |
| CHEMBL5090950 | — | IC50 | = | 1.05 | nM | 8.98 |
| CHEMBL5083589 | — | IC50 | = | 1.19 | nM | 8.92 |
| CHEMBL5078233 | — | IC50 | = | 2.78 | nM | 8.56 |
| CHEMBL5078651 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL5088990 | — | IC50 | = | 13.05 | nM | 7.88 |
| CHEMBL5089388 | — | IC50 | = | 37.85 | nM | 7.42 |