Assay Detail
Binding
CHEMBL5052861
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Binding affinity towards GLP-2 receptor in human HEK293 cells measured by fluorescence assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Peptide targeting gip and glp-2 receptors for treating bone disorders
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 8.46 | 10.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5089388 | — | — | 1 | 10.15 |
| CHEMBL5083589 | — | — | 1 | 9.36 |
| CHEMBL5090950 | — | — | 1 | 9.24 |
| CHEMBL5078651 | — | — | 1 | 8.98 |
| CHEMBL5075905 | — | — | 1 | 7.83 |
| CHEMBL5078233 | — | — | 1 | 7.82 |
| CHEMBL5072364 | — | — | 1 | 7.82 |
| CHEMBL5077951 | — | — | 1 | 7.64 |
| CHEMBL5088990 | — | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5089388 | — | IC50 | = | 0.07 | nM | 10.15 |
| CHEMBL5083589 | — | IC50 | = | 0.44 | nM | 9.36 |
| CHEMBL5090950 | — | IC50 | = | 0.57 | nM | 9.24 |
| CHEMBL5078651 | — | IC50 | = | 1.04 | nM | 8.98 |
| CHEMBL5075905 | — | IC50 | = | 14.74 | nM | 7.83 |
| CHEMBL5078233 | — | IC50 | = | 15.16 | nM | 7.82 |
| CHEMBL5072364 | — | IC50 | = | 15.05 | nM | 7.82 |
| CHEMBL5077951 | — | IC50 | = | 22.86 | nM | 7.64 |
| CHEMBL5088990 | — | IC50 | = | 53.01 | nM | 7.28 |