Assay Detail
Functional
CHEMBL5053009
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Antiproliferative activity against human MDA-MB-231 cells measured by WST-1 assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Foxm1 inhibitor compositions and methods of using the same
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.95 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5089499 | — | — | 1 | 6.52 |
| CHEMBL5079369 | — | — | 1 | 6.30 |
| CHEMBL5089001 | — | — | 1 | 6.30 |
| CHEMBL5078477 | — | — | 1 | 6.16 |
| CHEMBL5089867 | — | — | 1 | 6.05 |
| CHEMBL5077478 | — | — | 1 | 6.05 |
| CHEMBL5087866 | — | — | 1 | 5.96 |
| CHEMBL5075356 | — | — | 1 | 5.77 |
| CHEMBL5087067 | — | — | 1 | 5.40 |
| CHEMBL5075586 | — | — | 1 | 5.00 |
| CHEMBL5075271 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5089499 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL5079369 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL5089001 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL5078477 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL5089867 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL5077478 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL5087866 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL5075356 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL5087067 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL5075586 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL5075271 | — | IC50 | < | 5000.0 | nM | - |