Assay Detail
Binding
CHEMBL5053365
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Inhibition of wild-type CAPN5 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Compositions and methods for measuring and inhibiting calpain-5 activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.45 | 8.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92708 | CALPEPTIN | — | 1 | 8.08 |
| CHEMBL191881 | LEUPEPTIN | — | 1 | 6.78 |
| CHEMBL5088298 | — | — | 1 | 6.30 |
| CHEMBL5080053 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92708 | CALPEPTIN | IC50 | = | 8.35 | nM | 8.08 |
| CHEMBL191881 | LEUPEPTIN | IC50 | = | 165.0 | nM | 6.78 |
| CHEMBL5088298 | — | IC50 | = | 496.0 | nM | 6.30 |
| CHEMBL5080053 | — | IC50 | = | 24000.0 | nM | 4.62 |