Assay Detail
Functional
CHEMBL5053391
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Antiproliferative activity against human MDA-MB-157 cells after 72 hrs by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-157 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isoxazole derivatives targeting tacc3 as anticancer agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.99 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5085062 | — | — | 1 | 6.48 |
| CHEMBL3186037 | — | — | 1 | 5.74 |
| CHEMBL5080850 | — | — | 1 | 5.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5085062 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL3186037 | — | IC50 | = | 1820.0 | nM | 5.74 |
| CHEMBL5080850 | — | IC50 | = | 1820.0 | nM | 5.74 |