Assay Detail
Functional
CHEMBL5055480
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human Daudi cells assessed as cell growth inhibition incubated for 96 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Daudi |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Biological Evaluation of a Novel Series of Teriflunomide Derivatives as Potent Human Dihydroorotate Dehydrogenase Inhibitors for Malignancy Treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5079947 | — | — | 1 | 7.70 |
| CHEMBL5076703 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5079947 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5076703 | — | IC50 | = | 20.0 | nM | 7.70 |