Assay Detail
Binding
CHEMBL5055745
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human NPSR-Asn107 variant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-Activity Relationship Studies on Oxazolo[3,4-<i>a</i>]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent <i>In Vivo</i> Activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.80 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL469695 | — | — | 1 | 7.28 |
| CHEMBL470485 | — | — | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL469695 | — | Kd | = | 52.48 | nM | 7.28 |
| CHEMBL470485 | — | Kd | = | 489.78 | nM | 6.31 |