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Assay Detail

CHEMBL5056385

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of SARS-CoV-2 main protease by tandem mass spectrometry analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors.
Cui J, Jia J.
Eur J Med Chem (2021) 225 : 113789 -113789
PubMed 34438124 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.80 7.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL43612 JUGLONE 1 7.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL43612 JUGLONE IC50 = 15.75 nM 7.80