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Assay Detail

CHEMBL5058893

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
mBMMC chemotaxis
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histamine H4 receptor (CHEMBL5657)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Data for DCP probe JNJ-39758979
SGC Frankfurt
(2022)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.63 8.10

Assay Parameters

Parameter Type Value Units Text
Assay publication Assay publication - PMID: 14722321
Target protein type Target protein type - Mouse bone marrow mast cell (mBMMC)

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3236549 JNJ-39758979 2.0 1 8.10
CHEMBL5087167 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3236549 JNJ-39758979 IC50 = 8.0 nM 8.10
CHEMBL5087167 IC50 = 6900.0 nM 5.16