Assay Detail
Binding
CHEMBL5059548
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Horseradish Peroxidase (HRP) Fluorescence Assay
1
Total Activities
1
Compounds Tested
1
Activity Types
4
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe JNJ-9350
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.00 | 8.00 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Reactions were monitored continuously for 1hr on the BMG PHERAStar plate reader using an FI optic module (ex: 540 nm, em: 590 nm). |
| Assay publication | Assay publication | - | — | Slide 24-26 in JNJ-9350 Inhibitor for SMOX.pdf |
| Target protein length | Target protein length | - | — | human SMOX, Isoform 1 |
| Target protein type | Target protein type | - | — | Expression in E.coli |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5094181 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5094181 | — | Ki | = | 9.9 | nM | 8.00 |