Assay Detail
Binding
CHEMBL5059577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
BUB1 biochemical assay (low ATP)
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Mitotic checkpoint serine/threonine-protein kinase BUB1 (CHEMBL1772932) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe BAY 1816032
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.98 | 8.19 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | w/o preincubation |
| Assay publication | Assay publication | - | — | PMID: 30429199 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5084426 | — | — | 1 | 8.19 |
| CHEMBL5082184 | — | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5084426 | — | IC50 | = | 6.5 | nM | 8.19 |
| CHEMBL5082184 | — | IC50 | = | 1700.0 | nM | 5.77 |