Assay Detail
Binding
CHEMBL5069389
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Reverse ITC (compound as receptor). Domain start/stop: V50-P350
2
Total Activities
1
Compounds Tested
2
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Category | ITC assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
ITC assay results for EUbOPEN Chemical Probe Library
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.68 | 7.68 |
| Kd Error | 1 | - | - |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Protein Sequences | Protein Sequences | - | — | MHHHHHHSSGVDLGTENLYFQSMVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVP |
| Refseq Start/Stop | Refseq Start/Stop | - | — | V50-P350 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5087558 | — | — | 2 | 7.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5087558 | — | Kd | = | 21.0 | nM | 7.68 |
| CHEMBL5087558 | — | Kd Error | = | 0.16 | uM | - |