Assay Detail
Binding
CHEMBL5096466
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human His6-taged GSK-3beta assessed as substrate phosphorylation incubated for 30 mins using RRRPASVPPSPSLSRHSSHQRR peptide as substrate in presence of [gamma-32P]ATP by scintillation counter method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer's Disease Multitarget Drug Discovery?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.68 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4160653 | — | — | 1 | 6.05 |
| CHEMBL1910509 | — | — | 1 | 5.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4160653 | — | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL1910509 | — | IC50 | = | 4930.0 | nM | 5.31 |