Assay Detail
Binding
CHEMBL5096470
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Inhibition of HDAC1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer's Disease Multitarget Drug Discovery?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.84 | 7.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 7.14 |
| CHEMBL2018302 | TUBASTATIN A | — | 1 | 5.50 |
| CHEMBL4449010 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | IC50 | = | 73.0 | nM | 7.14 |
| CHEMBL2018302 | TUBASTATIN A | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL4449010 | — | IC50 | = | 12780.0 | nM | 4.89 |