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Assay Detail

CHEMBL5096525

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human KMM-1 cells assessed as inhibition of cell viability incubated for 72 hrs by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KMM-1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent Update on Targeting <i>c-MYC</i> G-Quadruplexes by Small Molecules for Anticancer Therapeutics.
Chaudhuri R, Bhattacharya S, Dash J, Bhattacharya S.
J Med Chem (2021) 64 : 42 -70
PubMed 33355454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.10 5.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5172233 1 5.38
CHEMBL1358584 1 4.81

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5172233 IC50 = 4130.0 nM 5.38
CHEMBL1358584 IC50 = 15600.0 nM 4.81