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Assay Detail

CHEMBL5096537

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human HEK293T cells assessed as inhibition of cell viability incubated for 72 hrs by MTS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type HEK-293T
Confidence 1 — Organism
Curated By Autocuration

Target

HEK-293T (CHEMBL3706568)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent Update on Targeting <i>c-MYC</i> G-Quadruplexes by Small Molecules for Anticancer Therapeutics.
Chaudhuri R, Bhattacharya S, Dash J, Bhattacharya S.
J Med Chem (2021) 64 : 42 -70
PubMed 33355454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.47 4.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5172233 1 4.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5172233 IC50 = 34000.0 nM 4.47