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Assay Detail

CHEMBL5096588

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human InsR expressed in mouse IGF1R knockout MEF cells assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type MEF
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Insulin receptor (CHEMBL1981)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Development and Therapeutic Potential of NUAKs Inhibitors.
Faisal M, Kim JH, Yoo KH, Roh EJ, Hong SS, Lee SH.
J Med Chem (2021) 64 : 2 -25
PubMed 33356242 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.92 7.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5182271 1 7.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5182271 Kd = 12.0 nM 7.92