Assay Detail
Binding
CHEMBL5096642
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at TRPM8 (unknown origin) ion channel
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transient receptor potential cation channel subfamily M member 8 (CHEMBL1075319) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Phytocannabinoid Pharmacology: Medicinal Properties of <i>Cannabis sativa</i> Constituents Aside from the "Big Two".
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.30 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2387541 | TETRAHYDROCANNABIVARIN | 2.0 | 1 | 7.70 |
| CHEMBL497318 | CANNABIGEROL | 2.0 | 1 | 6.80 |
| CHEMBL422704 | CANNABICHROMENE | — | 1 | 4.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2387541 | TETRAHYDROCANNABIVARIN | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL497318 | CANNABIGEROL | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL422704 | CANNABICHROMENE | IC50 | = | 40700.0 | nM | 4.39 |