Assay Detail
Binding
CHEMBL5096701
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human STING H232 mutant (139 to 378 residues) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by thermal shift assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
STING, a promising target for small molecular immune modulator: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 4.38 | 4.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5197229 | — | — | 1 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5197229 | — | Kd | = | 42000.0 | nM | 4.38 |