Assay Detail
Binding
CHEMBL5096703
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity to C-terminal domain STING (139 to 379 residues) in human PBMC assessed as IFN-beta secretion
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Stimulator of interferon genes protein (CHEMBL4523377) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
STING, a promising target for small molecular immune modulator: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.20 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5187053 | — | — | 1 | 6.89 |
| CHEMBL4440744 | — | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5187053 | — | EC50 | = | 130.0 | nM | 6.89 |
| CHEMBL4440744 | — | EC50 | = | 3100.0 | nM | 5.51 |