Assay Detail
Functional
CHEMBL5096891
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Antimalarial activity against Plasmodium falciparum D10 incubated for 48 hrs by [3H]hypoxanthine incorporation assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Metalloaminopeptidases of the Protozoan Parasite <i>Plasmodium falciparum</i> as Targets for the Discovery of Novel Antimalarial Drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.87 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3251700 | — | — | 1 | 5.10 |
| CHEMBL29292 | UBENIMEX | 2.0 | 1 | 4.83 |
| CHEMBL457092 | BESTATIN METHYL ESTER | — | 1 | 4.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3251700 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL29292 | UBENIMEX | IC50 | = | 14870.0 | nM | 4.83 |
| CHEMBL457092 | BESTATIN METHYL ESTER | IC50 | = | 20500.0 | nM | 4.69 |