Assay Detail
Binding
CHEMBL5097000
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of hedgehog signalling in mouse Shh Light II cells assessed as luciferase activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | Shh Light II |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Medulloblastoma drugs in development: Current leads, trials and drawbacks.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1201303 | PYRVINIUM | 4.0 | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1201303 | PYRVINIUM | IC50 | = | 10.0 | nM | 8.00 |