Assay Detail

CHEMBL5097013

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Functional

Antiproliferative activity against human D556 Med cells assessed as inhibition of cell proliferation measured after 4 days by WST-1 assay

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	D556 Med
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Medulloblastoma drugs in development: Current leads, trials and drawbacks.

Wen J, Hadden MK.
Eur J Med Chem (2021) 215 : 113268 -113268
PubMed 33636537 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.40	6.40

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5483015	ARSENIC TRIOXIDE	4.0	1	6.40

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5483015	ARSENIC TRIOXIDE	IC50	=	400.0	nM	6.40