Assay Detail
Binding
CHEMBL5097315
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Binding affinity to full length human recombinant PKAc assessed as dissociation constant
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent advances in development of hetero-bivalent kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 6.34 | 7.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5194339 | — | — | 1 | 7.42 |
| CHEMBL5199572 | — | — | 1 | 7.03 |
| CHEMBL5209851 | — | — | 1 | 5.80 |
| CHEMBL5198165 | — | — | 1 | 5.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5194339 | — | Kd | = | 38.0 | nM | 7.42 |
| CHEMBL5199572 | — | Kd | = | 94.0 | nM | 7.03 |
| CHEMBL5209851 | — | Kd | = | 1600.0 | nM | 5.80 |
| CHEMBL5198165 | — | Kd | = | 7700.0 | nM | 5.11 |