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Assay Detail

CHEMBL5097332

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Modulation of capsid disassembly in HIV 1 NL4-3 infected in human C8166 cells expressing LTR-luciferase reporter gene assessed as inhibition of viral protein disassembly
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Cell Type C8166
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

An insight on medicinal aspects of novel HIV-1 capsid protein inhibitors.
Sun L, Zhang X, Xu S, Huang T, Song S, Cherukupalli S, Zhan P, Liu X.
Eur J Med Chem (2021) 217 : 113380 -113380
PubMed 33751981 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.21 7.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2204009 1 7.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2204009 IC50 = 61.0 nM 7.21