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Assay Detail

CHEMBL5097604

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against human Cytomegalovirus infected in human fibroblast cells assessed as viral growth inhibition preincubated for 24 hrs with compound followed by viral infection by plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cytomegalovirus
Cell Type Fibroblast
Confidence 1 — Organism
Curated By Autocuration

Target

Cytomegalovirus (CHEMBL613134)
Type ORGANISM
Organism Cytomegalovirus

Publication

AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors.
Zhang G, Li S, Cheng KW, Chou TF.
Eur J Med Chem (2021) 219 : 113446 -113446
PubMed 33873056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2311578 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2311578 IC50 = 130.0 nM 6.89