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Assay Detail

CHEMBL5097607

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza A virus (A/Texas/04/2009 (H1N1)) infected in MDCK cells over expressing ST6Gal I assessed as inhibition of viral replication by plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors.
Zhang G, Li S, Cheng KW, Chou TF.
Eur J Med Chem (2021) 219 : 113446 -113446
PubMed 33873056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2311578 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2311578 EC50 = 30.0 nM 7.52