Assay Detail
Functional
CHEMBL5097885
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplasmodial activity against GHA chloroquine sensitive Plasmodium falciparum
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure activity relationship in β-carboline derived anti-malarial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.26 | 6.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1774691 | — | — | 1 | 6.01 |
| CHEMBL1774692 | — | — | 1 | 5.90 |
| CHEMBL1774693 | — | — | 1 | 5.77 |
| CHEMBL5204238 | — | — | 1 | 5.40 |
| CHEMBL1774689 | — | — | 1 | 5.16 |
| CHEMBL1774690 | — | — | 1 | 5.05 |
| CHEMBL5207239 | — | — | 1 | 4.60 |
| CHEMBL5196122 | — | — | 1 | 4.22 |
| CHEMBL5198214 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1774691 | — | IC50 | = | 970.0 | nM | 6.01 |
| CHEMBL1774692 | — | IC50 | = | 1260.0 | nM | 5.90 |
| CHEMBL1774693 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL5204238 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1774689 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL1774690 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL5207239 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL5196122 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL5198214 | — | IC50 | > | 64000.0 | nM | - |