Assay Detail
Functional
CHEMBL5098227
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Antileishmanial activity against Leishmania panamensis MHOM/CO/87/UA140-EGFP intracellular amastigotes infected in U-937 cells assessed as parasite growth inhibition measured after 72 hrs by flow cytometry analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania panamensis |
| Cell Type | U-937 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advancements in anti-leishmanial research: Synthetic strategies and structural activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.33 | 5.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5177826 | — | — | 1 | 5.49 |
| CHEMBL5199525 | — | — | 1 | 5.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5177826 | — | EC50 | = | 3240.0 | nM | 5.49 |
| CHEMBL5199525 | — | EC50 | = | 6720.0 | nM | 5.17 |