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Assay Detail

CHEMBL5098243

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antileishmanial activity against Leishmania infantum MCAN/ES/92/BCN83 intracellular amastigotes infected in mouse J774 macrophages assessed as inhibition of parasite growth incubated for 48 hrs by fluorometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania infantum
Cell Type J774
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania infantum (CHEMBL612848)
Type ORGANISM
Organism Leishmania infantum

Publication

Recent advancements in anti-leishmanial research: Synthetic strategies and structural activity relationships.
Gupta O, Pradhan T, Bhatia R, Monga V.
Eur J Med Chem (2021) 223 : 113606 -113606
PubMed 34171661 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.80 4.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL56234 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL56234 IC50 = 15790.0 nM 4.80