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Assay Detail

CHEMBL5098248

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of NPC1/VSV pseudotyped Ebola Viral Glycoprotein protein-protein interaction
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Ebolavirus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction.
Morales-Tenorio M, Ginex T, Cuesta-Geijo MÁ, Campillo NE, Muñoz-Fontela C, Alonso C, Delgado R, Gil C.
Eur J Med Chem (2021) 223 : 113654 -113654
PubMed 34175537 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.35 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2323039 1 6.89
CHEMBL2323275 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2323039 IC50 = 130.0 nM 6.89
CHEMBL2323275 IC50 = 1600.0 nM 5.80