Assay Detail
Functional
CHEMBL5098519
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Antiviral activity against DENV2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A short survey of dengue protease inhibitor development in the past 6 years (2015-2020) with an emphasis on similarities between DENV and SARS-CoV-2 proteases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.60 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5206072 | — | — | 1 | 5.92 |
| CHEMBL4456898 | — | — | 1 | 5.62 |
| CHEMBL5179918 | — | — | 1 | 5.46 |
| CHEMBL1535689 | — | — | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5206072 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4456898 | — | EC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL5179918 | — | EC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL1535689 | — | EC50 | = | 4200.0 | nM | 5.38 |