Assay Detail
Binding
CHEMBL5098532
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Inhibition of DENV2 pro
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | dengue virus type 2 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A short survey of dengue protease inhibitor development in the past 6 years (2015-2020) with an emphasis on similarities between DENV and SARS-CoV-2 proteases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.38 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3740727 | — | — | 1 | 7.75 |
| CHEMBL5177343 | — | — | 1 | 6.30 |
| CHEMBL5179425 | — | — | 1 | 6.02 |
| CHEMBL4522006 | — | — | 1 | 5.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3740727 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL5177343 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL5179425 | — | IC50 | = | 950.0 | nM | 6.02 |
| CHEMBL4522006 | — | IC50 | = | 3600.0 | nM | 5.44 |