Assay Detail
Binding
CHEMBL5098540
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Inhibition of DENV2 His tagged NS2B (48 to 95 residues)/NS3 (1 to 185 residues) protein protein interaction
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | dengue virus type 2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A short survey of dengue protease inhibitor development in the past 6 years (2015-2020) with an emphasis on similarities between DENV and SARS-CoV-2 proteases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.82 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5483017 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5483017 | — | IC50 | = | 15000.0 | nM | 4.82 |