Assay Detail
Binding
CHEMBL5098682
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full length human GSK3beta in the presence of ATP at Km concentration
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.93 | 6.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5170524 | — | — | 1 | 6.51 |
| CHEMBL3663760 | — | — | 1 | 5.85 |
| CHEMBL5207871 | — | — | 1 | 5.82 |
| CHEMBL5197170 | — | — | 1 | 5.80 |
| CHEMBL5198038 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5170524 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL3663760 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL5207871 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5197170 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL5198038 | — | IC50 | = | 2100.0 | nM | 5.68 |