Assay Detail
Functional
CHEMBL5098752
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Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From natural products to HDAC inhibitors: An overview of drug discovery and design strategy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.72 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5173807 | — | — | 1 | 6.72 |
| CHEMBL62381 | SODIUM BUTYRATE | 2.0 | 1 | - |
| CHEMBL109 | VALPROIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5173807 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL62381 | SODIUM BUTYRATE | IC50 | = | 500000.0 | nM | - |
| CHEMBL109 | VALPROIC ACID | IC50 | = | 230000.0 | nM | - |