Assay Detail
Binding
CHEMBL5098756
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Inhibition of HDAC1 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
From natural products to HDAC inhibitors: An overview of drug discovery and design strategy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.94 | 7.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1173445 | LARGAZOLE | — | 1 | 7.94 |
| CHEMBL109 | VALPROIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1173445 | LARGAZOLE | IC50 | = | 11.4 | nM | 7.94 |
| CHEMBL109 | VALPROIC ACID | IC50 | = | 400000.0 | nM | - |