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Assay Detail

CHEMBL5098778

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Functional
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

From natural products to HDAC inhibitors: An overview of drug discovery and design strategy.
Qiu X, Zhu L, Wang H, Tan Y, Yang Z, Yang L, Wan L.
Bioorg Med Chem (2021) 52 : 116510 -116510
PubMed 34826681 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.72 6.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5173807 1 6.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5173807 IC50 = 190.0 nM 6.72