Assay Detail
Binding
CHEMBL5098783
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Inhibition of HDAC in Sprague-Dawley rat hepatocytes using Fluor de Lys as substrate incubated for 15 mins by fluorometric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | Hepatocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
From natural products to HDAC inhibitors: An overview of drug discovery and design strategy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.74 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL57226 | — | — | 1 | 7.85 |
| CHEMBL46942 | — | — | 1 | 7.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL57226 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL46942 | — | IC50 | = | 24.0 | nM | 7.62 |